1st Year GNM KARNATAKA Anatomy, Physiology and Microbiology FEBRUARY 2025

KARNATAKA STATE DIPLOMA IN NURSING EXAMINATION BOARD
GNM THEORY EXAMINATION – FEBRUARY 2025
1st YEAR - BIO-SCIENCE - PAPER – I
(Anatomy, Physiology and Microbiology)

Duration: 3 Hours 
Max.Marks:75

Answer all questions.
Figures in the right-hand margin indicate marks

I.    Give the meaning of the following

[ 1x4 = 4 ]
1. Immunity 
2. Osmosis 
3. Abduction 
4. Hypersensitivity

Answer :

1) Immunity

Ability of the body to resist and defend itself against disease-producing microorganisms and harmful foreign substances.


2) Osmosis

Movement of water molecules from an area of low solute concentration to an area of high solute concentration through a semi-permeable membrane.


3) Abduction

Movement of a body part away from the midline of the body.
(e.g. lifting the arm sideways away from body)


4) Hypersensitivity

Exaggerated or abnormal immune response of the body to an antigen, which results in tissue damage or allergic reaction.



II. Fill in the blanks

[ 1x4 = 4 ]
5. __________ is covering membrane of the Brain 
6. Insulin is secreted by _______ cells of pancreas 
7. ____________ is the functional unit of the kidney 
8. _________ is the innermost layer of the uterus

Answer :

5.      Meninges is covering membrane of the brain.

6.      Insulin is secreted by Beta (β) cells of pancreas.

7.      Nephron is the functional unit of the kidney.

8.      Endometrium is the innermost layer of the uterus.



III. Write short notes for any FOUR of the following

[ 4 x 4= 16 ]
9. Classification of bacteria 
10. Structure of liver 
11. Structure of lungs 
12. Structure of ovary 
13. Ball and socket joint

Answer :

9) Classification of Bacteria

Bacteria are classified on the basis of:

• Shape (morphology)
– Cocci → spherical
– Bacilli → rod shaped
– Vibrios → comma shaped
– Spirilla → spiral shaped

• Gram Staining
– Gram Positive bacteria
– Gram Negative bacteria

• Oxygen Requirement
– Aerobic (require oxygen)
– Anaerobic (grow without oxygen)

• Motility
– Motile (with flagella)
– Non-motile


10) Structure of Liver

  • Largest gland in the body.
  • Located in right upper abdomen below diaphragm.
  • Has two main lobes: Right and Left.
  • Functional unit → Liver lobule.
  • Lobule contains hepatocytes arranged around a central vein.
  • Contains portal triad: branch of hepatic artery, portal vein & bile duct.
  • Covered by a fibrous capsule called Glisson’s capsule.

11) Structure of Lungs

  • Pair of spongy, elastic organs in thoracic cavity.
  • Right lung = 3 lobes; Left lung = 2 lobes (due to heart).
  • Surrounded by pleural membrane: parietal & visceral pleura.
  • Inside lungs: bronchi → bronchioles → alveoli.
  • Alveoli are thin-walled air sacs where gas exchange occurs.

12) Structure of Ovary

  • Ovaries are paired female reproductive glands.
  • Located in pelvic cavity on both sides of uterus.
  • Outer layer → Cortex (contains ovarian follicles).
  • Inner layer → Medulla (contains blood vessels & nerves).
  • Forms Graafian follicle, ovum, and corpus luteum.
  • Produces hormones: estrogen & progesterone.

13) Ball and Socket Joint

  • A type of synovial joint.
  • Rounded head of one bone fits into cup-shaped socket of another bone.
  • Allows movement in all directions including rotation.
  • Examples: Shoulder joint (humerus + scapula), Hip joint (femur + acetabulum).


IV.  Answer the following

[ 3+4 = 7 ]  
14. List the organs of   nervous system 
15. Describe the structure of Brain with a neat labelled diagram 
[ 3+5 = 8 ] 
16. List the bones of the axial skeletal system 
17. Explain the structure of sternum

 Answer :

14) List the organs of Nervous System (3 marks)

Main organs of nervous system are:

  • Brain
  • Spinal Cord
  • Cranial Nerves
  • Spinal Nerves
  • Sense organs (Eye, Ear, Nose, Tongue, Skin)

15) Structure of Brain (with neat labelled diagram) (4 marks)

  • Brain lies inside the cranial cavity.
  • Protected by skull and meninges (Dura mater, Arachnoid mater, Pia mater).
  • It is divided into 3 major parts:

1) Cerebrum
Largest part, divided into right & left hemispheres.
Controls intelligence, memory, emotions & voluntary movements.

2) Cerebellum
Located below cerebrum at back.
Controls balance, posture & coordination.

3) Brainstem (Midbrain, Pons, Medulla)
Controls vital functions like heartbeat, respiration & BP.

Simple labelled diagram style to draw in exam:

    


16) List the bones of Axial Skeletal System (3 marks)

Axial skeleton includes bones along the central axis of body:

  • Skull bones
  • Hyoid bone
  • Vertebral column (33 vertebrae)
  • Sternum
  • 12 pairs of ribs (Rib cage)

17) Structure of Sternum (5 marks)

  • Sternum is a long flat bone present in anterior midline of chest.
  • It forms the front part of thoracic cage.
  • It protects heart & mediastinum.

Parts of Sternum:

  1. Manubrium – upper portion
  2. Body / Gladiolus – middle long portion
  3. Xiphoid process – lower cartilaginous part (ossifies in adulthood)

Attachments:

  • Manubrium articulates with clavicles & 1st rib.
  • Body articulates with costal cartilages of 2nd to 7th ribs.


V. State the following statement is True / False

[ 1x4 = 4 ]
18. Stapes is the smallest bone of our body 
19. Tetanus is caused by clostridium tetani 
20. Vagus nerve is the ninth cranial nerve 
21. Sources of infection within the body are called exogenous

Answer :

  1. Stapes is the smallest bone of our bodyTrue
  2. Tetanus is caused by Clostridium tetaniTrue
  3. Vagus nerve is the ninth cranial nerveFalse
    (Vagus nerve is the 10th cranial nerve)
  4. Sources of infection within the body are called exogenousFalse
    (Within the body = endogenous)


VI.  Write short notes for any THREE of the following

[ 4x4 = 16 ]
22. Functions of kidney 
23. Physiology of hearing 
24. Metabolism of proteins 
25. Scope of microbiology in nursing 
26. Sources of infection

Answer :

22) Functions of Kidney

  • Kidneys filter blood and form urine.
  • Maintain water & electrolyte balance.
  • Regulate acid–base balance of body.
  • Excrete waste products like urea, uric acid & creatinine.
  • Produce hormones: Erythropoietin (RBC formation) & Renin (BP control).
  • Help in regulation of blood pressure.

23) Physiology of Hearing

  • Sound waves enter external ear → eardrum vibrates.
  • Vibrations pass through ear ossicles (malleus → incus → stapes).
  • Stapes pushes oval window → sound waves enter cochlea.
  • Fluid movement in cochlea stimulates organ of Corti.
  • Hair cells convert vibrations into nerve impulses.
  • Impulses travel through auditory nerve to brain (temporal lobe) for interpretation of sound.

24) Metabolism of Proteins

  • Proteins are broken down into amino acids during digestion.
  • Amino acids are absorbed into blood and taken to liver.
  • In liver they undergo transamination & deamination.
  • Ammonia formed is converted into urea (urea cycle) and excreted by kidneys.
  • Amino acids are used for: body growth, repair of tissues, enzymes, hormones & energy if required.

25) Scope of Microbiology in Nursing

  • Helps nurses to understand microorganisms and diseases.
  • Helps in prevention of hospital-acquired infections.
  • Guides proper sterilization & disinfection techniques.
  • Helps in infection control practices (hand washing, PPE, isolation).
  • Helps in safe handling of specimens for lab tests.
  • Improves quality of nursing care and patient safety.

26) Sources of Infection

  • Human beings (infected persons & carriers)
  • Animals (zoonotic infections)
  • Water (contaminated water)
  • Food (spoiled food)
  • Air / droplets
  • Soil (spore forming organisms)
  • Fomites ( contaminated objects like clothes, instruments)


VII.  Answer the following

[3 + 5 = 8 ]
27. List is endocrine gland 
28. Explain the hormones secreted by anterior pituitary gland 
[ 4+4 = 8 ]
29. Draw a neat diagram of cell 
30. Explain stages of cell division

Answer :

27) List the Endocrine Glands (3 marks)

  • Pituitary gland
  • Pineal gland
  • Thyroid gland
  • Parathyroid glands
  • Adrenal glands
  • Pancreas (Islets of Langerhans)
  • Gonads → Testes / Ovaries
  • Thymus

28) Hormones Secreted by Anterior Pituitary Gland (5 marks)

The anterior pituitary secretes the following important hormones:

Hormone

Full Form

Function (short)

GH

Growth Hormone

Body growth, metabolism

TSH

Thyroid Stimulating Hormone

Stimulates thyroid hormone secretion

ACTH

Adrenocorticotropic Hormone

Stimulates adrenal cortex

FSH

Follicle Stimulating Hormone

Gamete formation (ovum / sperm)

LH

Luteinizing Hormone

Ovulation / testosterone secretion

PRL

Prolactin

Milk secretion in breast


29) Neat Diagram of Cell (for exam) (4 marks)

How to draw simple cell diagram (label these parts):

Labels to write:

  • Cell membrane
  • Cytoplasm
  • Nucleus
  • Mitochondria
  • Ribosomes
  • Endoplasmic Reticulum (ER)

(This is acceptable for 4 marks — simple & clean.)


30) Stages of Cell Division (4 marks)

Cell division occurs mainly by mitosis.

Stages of Mitosis:

  1. Prophase – Chromosomes appear, nuclear membrane disappears.
  2. Metaphase – Chromosomes line up in center of cell.
  3. Anaphase – Sister chromatids separate and move to opposite poles.
  4. Telophase – Nuclear membrane reforms around each set of chromosomes.
  5. Cytokinesis – Cytoplasm divides → forms two daughter cells.

 


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